CD55 and ADGRE5

Number of citations of the paper that reports this interaction (PubMedID 10540231)
18

Data Source:
HPRD (in vivo)

		CD55	ADGRE5
Description		CD55 molecule (Cromer blood group)	adhesion G protein-coupled receptor E5
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Cell Plasma Membrane Cell Surface Transport Vesicle Secretory Granule Membrane Anchored Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Raft Extracellular Exosome Ficolin-1-rich Granule Membrane	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Lipid Binding	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Complement Activation, Classical Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD4-positive, Alpha-beta T Cell Cytokine Production Neutrophil Degranulation Innate Immune Response Respiratory Burst Negative Regulation Of Complement Activation Viral Entry Into Host Cell Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation	Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Degranulation
Pathways		Class B/2 (Secretin family receptors) Neutrophil degranulation COPI-mediated anterograde transport Regulation of Complement cascade	Class B/2 (Secretin family receptors) Neutrophil degranulation
Drugs		Chloramphenicol
Diseases		Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
GWAS		Blood protein levels ( 30072576 29875488 28240269) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Blood protein levels ( 28240269)
Interacting Genes		6 interacting genes: ADGRE5 CD14 CR1 FYN GPLD1 LCK	4 interacting genes: CD55 GCC1 HNRNPD XRN1
Entrez ID		1604	976
HPRD ID		00500	03130
Ensembl ID		ENSG00000196352	ENSG00000123146
Uniprot IDs		B1AP13 P08174	P48960
PDB IDs		1H03 1H04 1H2P 1H2Q 1M11 1NWV 1OJV 1OJW 1OJY 1OK1 1OK2 1OK3 1OK9 1UOT 1UPN 2C8I 2QZD 2QZF 2QZH 3IYP 3J24 5FOA 6ILJ 6ILK	2BOU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?