DAB1 and DAZAP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DAB1	DAZAP2
Description		DAB adaptor protein 1	DAZ associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Brush Border Postsynaptic Density Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Apical Part Of Cell Perinuclear Region Of Cytoplasm	Cytoplasm Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding Phosphatidylinositol 3-kinase Binding	Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding
	Biological Process	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Axon Guidance Midgut Development Adult Walking Behavior Dendrite Development Ventral Spinal Cord Development Cerebellum Structural Organization Hippocampus Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Radial Glia Guided Migration Of Purkinje Cell Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Golgi Localization Lateral Motor Column Neuron Migration	Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Reelin signalling pathway
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alzheimer's disease progression score ( 29860282) Bulimia nervosa ( 23568457) Cardiac troponin-I levels ( 31014085) Coronary artery disease ( 29472232) Household income (MTAG) ( 31844048) Immune reponse to smallpox (secreted IL-10) ( 22610502) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Kawasaki disease ( 21221998) Lateral orbital frontal cortex volume ( 31530798) Logical memory (delayed recall) in normal cognition ( 29274321) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Pubertal anthropometrics ( 23449627) Risk-taking tendency (4-domain principal component model) ( 30643258) Waist circumference ( 28552196) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		75 interacting genes: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MAPK14 MBNL1 MBNL3 MYO6 NAF1 NTAQ1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RAMAC RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SOCS6 SOCS7 SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR ZBTB32 ZC3H10 ZCCHC10 ZNF488	91 interacting genes: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FBN3 GPSM1 HGS HIP1 INCA1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MAGED1 MED31 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBM11 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPTIN2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TENT5B TENT5C TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE3A UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		1600	9802
HPRD ID		04582	08463
Ensembl ID		ENSG00000173406	ENSG00000183283
Uniprot IDs		O75553	A0A024R110 Q15038
PDB IDs
Enriched GO Terms of Interacting Partners?
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