EXOC8 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (two hybrid)

		EXOC8	EFHC2
Description		exocyst complex component 8	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm	Microtubule
	Molecular Function	Protein Binding Ral GTPase Binding Phosphatidylinositol Binding	Calcium Ion Binding Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)	Mean arterial pressure ( 29403010)
Interacting Genes		21 interacting genes: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA SASH1 TADA2A ULK1 USHBP1	37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		149371	80258
HPRD ID		09943	06540
Ensembl ID		ENSG00000116903	ENSG00000183690
Uniprot IDs		Q8IYI6	Q5JST6
PDB IDs			2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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