EXOC8 and MBIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		EXOC8	MBIP
Description		exocyst complex component 8	MAP3K12 binding inhibitory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Leading Edge Perinuclear Region Of Cytoplasm	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus Cytosol
	Molecular Function	Protein Binding Ral GTPase Binding Phosphatidylinositol Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Cellular Protein Localization	Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Histone H3 Acetylation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	HATs acetylate histones
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)	Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335)
Interacting Genes		21 interacting genes: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA SASH1 TADA2A ULK1 USHBP1	42 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SMARCB1 STX11 TGIF2LY TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		149371	51562
HPRD ID		09943	14368
Ensembl ID		ENSG00000116903	ENSG00000151332
Uniprot IDs		Q8IYI6	B2RCV0 Q9NS73
PDB IDs
Enriched GO Terms of Interacting Partners?
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