CSTA and PI3

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

		CSTA	PI3
Description		cystatin A	peptidase inhibitor 3
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GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleoplasm Cytoplasm Cytosol	Cornified Envelope Extracellular Region Cytosol Extracellular Matrix
	Molecular Function	Protease Binding Cysteine-type Endopeptidase Inhibitor Activity Protein Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Structural Constituent Of Epidermis
	Biological Process	Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Keratinocyte Differentiation Negative Regulation Of Proteolysis Cornification Cell-cell Adhesion	Copulation Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Antimicrobial Humoral Response Cornification
Pathways		Formation of the cornified envelope	Antimicrobial peptides Formation of the cornified envelope
Drugs
Diseases
GWAS		Calcium levels ( 25972035 29403010 20705733)	Bipolar disorder ( 31043756) Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		12 interacting genes: CTSB CTSH CTSL DSP EVPL IVL KRT1 LORICRIN PI3 PTN UCHL5 ZDHHC17	5 interacting genes: CELA1 CSTA EVPL KRT1 LORICRIN
Entrez ID		1475	5266
HPRD ID		01697	15947
Ensembl ID		ENSG00000121552	ENSG00000124102
Uniprot IDs		P01040	P19957
PDB IDs		1CYU 1CYV 1DVC 1DVD 1GD3 1GD4 1N9J 1NB3 1NB5 3K9M 3KFQ 3KSE	1FLE 2REL 6ATU
Enriched GO Terms of Interacting Partners?
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