CSPG4 and GRIP1

Number of citations of the paper that reports this interaction (PubMedID 12458226)
36

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		CSPG4	GRIP1
Description		chondroitin sulfate proteoglycan 4	glutamate receptor interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Apical Plasma Membrane Lamellipodium Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Protein Kinase Binding	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Receptor Signaling Complex Scaffold Activity Glucocorticoid Receptor Binding Androgen Receptor Binding
	Biological Process	Activation Of MAPK Activity Angiogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Proliferation Glial Cell Migration Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Intracellular Signal Transduction Tissue Remodeling Positive Regulation Of Peptidyl-tyrosine Phosphorylation	Positive Regulation Of Signal Transduction Dendrite Development Androgen Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Transcription, DNA-templated Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1	Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Intraocular pressure ( 29617998) Simvastatin-induced myopathy ( 31220337)	Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		9 interacting genes: ATF7IP BCAR1 C1QA CDC42 GRIP1 GRIP2 MPDZ PTK2 TNK2	35 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EFNA5 EFNB1 EFNB2 EP300 ESR1 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 IRF3 NCOA6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR
Entrez ID		1464	23426
HPRD ID		03105	19086
Ensembl ID		ENSG00000173546	ENSG00000155974
Uniprot IDs		Q6UVK1	Q9Y3R0
PDB IDs			2JIL
Enriched GO Terms of Interacting Partners?
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