CSPG4

Description		chondroitin sulfate proteoglycan 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Apical Plasma Membrane Lamellipodium Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Kinase Binding
	Biological Process	Activation Of MAPK Activity Angiogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Proliferation Glial Cell Migration Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Intracellular Signal Transduction Tissue Remodeling Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Intraocular pressure ( 29617998) Simvastatin-induced myopathy ( 31220337)
Interacting Genes		9 interacting genes: ATF7IP BCAR1 C1QA CDC42 GRIP1 GRIP2 MPDZ PTK2 TNK2
Entrez ID		1464
HPRD ID		03105
Ensembl ID		ENSG00000173546
Uniprot IDs		Q6UVK1
PDB IDs
Enriched GO Terms of Interacting Partners?
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