HAPLN3 and CRTC3

		HAPLN3	CRTC3
Description		hyaluronan and proteoglycan link protein 3	CREB regulated transcription coactivator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Matrix	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Hyaluronic Acid Binding	Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	Skeletal System Development Cell Adhesion Central Nervous System Development	Viral Process Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis
Pathways			Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs		Hyaluronic acid
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340) Lung cancer in ever smokers ( 28604730) Multiple keratinocyte cancers ( 28081215)	Chromium levels ( 26025379) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: CRTC3	11 interacting genes: AEN C15orf32 HAPLN3 KLHL12 RCCD1 RGMA SIK2 TICRR UNC45A WDR93 YWHAG
Entrez ID		145864	64784
HPRD ID		13629	13384
Ensembl ID		ENSG00000140511	ENSG00000140577
Uniprot IDs		A0A024RC58 A8K7T8 H3BTH8 Q96S86	Q6UUV7 Q8TEF4
PDB IDs
Enriched GO Terms of Interacting Partners?
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