SREK1 and TRA2B

Number of citations of the paper that reports this interaction (PubMedID 14559993)
14

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SREK1	TRA2B
Description		splicing regulatory glutamic acid and lysine rich protein 1	transformer 2 beta homolog
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Cell Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Glucose Stimulus Embryonic Brain Development
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		55 interacting genes: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RACK1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	28 interacting genes: CDK6 CLK1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 USP13 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		140890	6434
HPRD ID		18043	04097
Ensembl ID		ENSG00000153914	ENSG00000136527
Uniprot IDs		Q8WXA9	P62995
PDB IDs			2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
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