TRA2B and HNRNPA1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		TRA2B	HNRNPA1
Description		transformer 2 beta homolog	heterogeneous nuclear ribonucleoprotein A1
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GO Annotations	Cellular Component	Cell Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding	Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding MiRNA Binding Pre-mRNA Binding Telomeric Repeat-containing RNA Binding G-rich Strand Telomeric DNA Binding
	Biological Process	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Glucose Stimulus Embryonic Brain Development	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus Fibroblast Growth Factor Receptor Signaling Pathway Viral Process RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Glucose Starvation MRNA Transport Nuclear Export Import Into Nucleus Regulation Of RNA Metabolic Process Cellular Response To Sodium Arsenite
Pathways		mRNA Splicing - Major Pathway	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		28 interacting genes: CDK6 CLK1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 USP13 YTHDC1 YWHAG YWHAZ ZRANB2	40 interacting genes: ABHD16A APP BCL2L1 CLK1 ERG ESR1 FEN1 H3-4 H3C1 HIPK3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 RPS6KB2 SAFB SNRNP200 SREK1 SRPK1 SRPK2 SUFU TFEC TNPO1 TRA2B TRAF6 TTF2 XIAP XRN1
Entrez ID		6434	3178
HPRD ID		04097	01242
Ensembl ID		ENSG00000136527	ENSG00000135486
Uniprot IDs		P62995	A0A024RAZ7 A0A024RB53 P09651
PDB IDs		2CQC 2KXN 2RRA 2RRB	1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1 4YOE 5MPG 5MPL 5ZGD 5ZGL 6BXX 6DCL 6J60
Enriched GO Terms of Interacting Partners?
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