ZFP28 and PRKRA

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		ZFP28	PRKRA
Description		ZFP28 zinc finger protein	protein activator of interferon induced protein kinase EIF2AK2
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GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex
	Molecular Function	DNA Binding Metal Ion Binding	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Protein Phosphorylation Immune Response Negative Regulation Of Cell Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Catalytic Activity Skeletal System Morphogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Generic Transcription Pathway	MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS			Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		5 interacting genes: C8orf33 HMOX2 KDM1A PPP2CB PRKRA	21 interacting genes: AGO2 CEBPZ CEP126 COPS6 DICER1 EIF2AK2 GDF9 LYAR NKRF POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZNF746
Entrez ID		140612	8575
HPRD ID		15725	04573
Ensembl ID		ENSG00000196867	ENSG00000180228
Uniprot IDs		Q8NHY6	B4DJC7 O75569
PDB IDs		2EM2 2EM3 2EM4 2EMJ 2EMK 2EML 2EN9 2ENH 2EOH 2EP0 2EPX 2EPZ 2YTM	2DIX
Enriched GO Terms of Interacting Partners?
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