NACC2 and MTA2

Number of citations of the paper that reports this interaction (PubMedID 22926524)
6

Data Source:
BioGRID (pull down)

		NACC2	MTA2
Description		NACC family member 2	metastasis associated 1 family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleolus Mitochondrion	Histone Deacetylase Complex Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Membrane NuRD Complex Protein-containing Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Protein-containing Complex Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation Histone Deacetylation Cellular Protein-containing Complex Localization Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Assembly Or Disassembly Regulation Of Fibroblast Migration Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) SjÃ¶gren's syndrome ( 28076899) Ulcerative colitis ( 28067908)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: EPS8 HDAC2 MTA1 MTA2 MTA3	22 interacting genes: APPL1 APPL2 BCL11B ESR1 FKBP3 H3-4 HDAC2 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN SUMO2 TP53 TSC22D3 UBE3C YY1
Entrez ID		138151	9219
HPRD ID		09831	07233
Ensembl ID		ENSG00000148411	ENSG00000149480
Uniprot IDs		A0A024R8I0 Q96BF6	A0A024R534 O94776
PDB IDs
Enriched GO Terms of Interacting Partners?
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