CR2 and IFITM1

Number of citations of the paper that reports this interaction (PubMedID 1383329)
73

Data Source:
HPRD (in vivo)

		CR2	IFITM1
Description		complement C3d receptor 2	interferon induced transmembrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Extracellular Exosome	Plasma Membrane Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Virus Receptor Activity Complement Binding DNA Binding Complement Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Complement Receptor Mediated Signaling Pathway Immune Response Complement Activation, Classical Pathway B Cell Differentiation Regulation Of Complement Activation B Cell Proliferation Innate Immune Response Viral Entry Into Host Cell	Ossification Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Response To Virus Negative Regulation Of Cell Migration Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Viral Entry Into Host Cell Regulation Of Immune Response Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Regulation of Complement cascade	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717) Systemic sclerosis ( 29293537) Type 2 diabetes ( 21490949)
Interacting Genes		10 interacting genes: ANXA6 C3 CD19 CR1 FCER2 FHOD1 HNRNPU IFITM1 IFNA1 TP53	3 interacting genes: ABHD16A CD81 CR2
Entrez ID		1380	8519
HPRD ID		00399	05122
Ensembl ID		ENSG00000117322	ENSG00000185885
Uniprot IDs		P20023	A0A024R210 P13164
PDB IDs		1GHQ 1LY2 1W2R 1W2S 2ATY 2GSX 3OED
Enriched GO Terms of Interacting Partners?
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