TSACC and FOXP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TSACC	FOXP2
Description		TSSK6 activating cochaperone	forkhead box P2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nuclear Chromatin
	Molecular Function	Protein Binding Chaperone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Androgen Receptor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Skeletal Muscle Tissue Development Post-embryonic Development Cerebellum Development Caudate Nucleus Development Putamen Development Cerebral Cortex Development Response To Testosterone Vocal Learning Camera-type Eye Development Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development Smooth Muscle Tissue Development Righting Reflex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Innate Vocalization Behavior
Pathways
Drugs
Diseases			Speech-language disorder 1 (SPCH1)
GWAS			Adventurousness ( 30643258) Age at first birth ( 27798627) Attention deficit hyperactivity disorder ( 30478444) Attention deficit hyperactivity disorder or cannabis use ( 30610198) Beard thickness ( 26926045) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 28892062 25673413) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Crohn's disease ( 22936669) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Drug experimentation measurement ( 30718321) Feeling tense ( 29500382) Gastroesophageal reflux disease ( 31527586) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Household income (MTAG) ( 31844048) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Irritable mood ( 29500382) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Multisite chronic pain ( 31194737) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Pelvic organ prolapse (moderate/severe) ( 26545240) Self-reported risk-taking behaviour ( 30271922 30181555) Serum sulfate level ( 27412988) Sleep duration ( 27992416) Sleep duration (short sleep) ( 30846698) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Urate levels in obese individuals ( 25811787) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)
Interacting Genes		3 interacting genes: DTNB FOXP2 KDM1A	13 interacting genes: CCNC CTBP1 CTBP2 FAM124A FOXP1 FOXP4 MAPK3 PIN1 RPIA SDCBP SP4 TLE5 TSACC
Entrez ID		128229	93986
HPRD ID		10252	05611
Ensembl ID		ENSG00000163467	ENSG00000128573
Uniprot IDs		Q96A04 V9GYT6	B7ZLK5 O15409 Q8N6B5 Q8N6B6 X5D2H2
PDB IDs			2A07 2AS5
Enriched GO Terms of Interacting Partners?
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