FOXP2 and FOXP4

Number of citations of the paper that reports this interaction (PubMedID 14701752)
107

Data Source:
HPRD (two hybrid, in vitro)

		FOXP2	FOXP4
Description		forkhead box P2	forkhead box P4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nuclear Chromatin
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Androgen Receptor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Skeletal Muscle Tissue Development Post-embryonic Development Cerebellum Development Caudate Nucleus Development Putamen Development Cerebral Cortex Development Response To Testosterone Vocal Learning Camera-type Eye Development Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development Smooth Muscle Tissue Development Righting Reflex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Innate Vocalization Behavior	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Speech-language disorder 1 (SPCH1)
GWAS		Adventurousness ( 30643258) Age at first birth ( 27798627) Attention deficit hyperactivity disorder ( 30478444) Attention deficit hyperactivity disorder or cannabis use ( 30610198) Beard thickness ( 26926045) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 28892062 25673413) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Crohn's disease ( 22936669) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Drug experimentation measurement ( 30718321) Feeling tense ( 29500382) Gastroesophageal reflux disease ( 31527586) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Household income (MTAG) ( 31844048) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Irritable mood ( 29500382) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Multisite chronic pain ( 31194737) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Pelvic organ prolapse (moderate/severe) ( 26545240) Self-reported risk-taking behaviour ( 30271922 30181555) Serum sulfate level ( 27412988) Sleep duration ( 27992416) Sleep duration (short sleep) ( 30846698) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Urate levels in obese individuals ( 25811787) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)	Chronotype ( 30696823) EGFR mutation-positive lung adenocarcinoma ( 27501781) Metabolite levels ( 23823483) Non-small cell lung cancer ( 31326317) Prostate cancer ( 20676098 31562322)
Interacting Genes		13 interacting genes: CCNC CTBP1 CTBP2 FAM124A FOXP1 FOXP4 MAPK3 PIN1 RPIA SDCBP SP4 TLE5 TSACC	3 interacting genes: FOXP1 FOXP2 XAGE2
Entrez ID		93986	116113
HPRD ID		05611	10600
Ensembl ID		ENSG00000128573	ENSG00000137166
Uniprot IDs		B7ZLK5 O15409 Q8N6B5 Q8N6B6 X5D2H2	Q8IVH2
PDB IDs		2A07 2AS5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?