SOCS4 and MPP5

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		SOCS4	MPP5
Description		suppressor of cytokine signaling 4	membrane palmitoylated protein 5
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GO Annotations	Cellular Component	Phosphatidylinositol 3-kinase Complex	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding ATP Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity
Pathways		RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Tight junction interactions
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: CNMD EGFR LDHAL6B MDFIC MPP5 NR4A1 PLPP6 SPRY1 TNK2 VWF	8 interacting genes: ARF6 CRB3 LIN7A MPP4 NEK9 PARD6B PATJ SOCS4
Entrez ID		122809	64398
HPRD ID		18084	09508
Ensembl ID		ENSG00000180008	ENSG00000072415
Uniprot IDs		Q5H9R6 Q8WXH5	Q658X5 Q8N3R9
PDB IDs		2IZV	1Y76 3UIT 4UU5 4UU6 4WSI
Enriched GO Terms of Interacting Partners?
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