EXOSC6 and DNAJC30

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		EXOSC6	DNAJC30
Description		exosome component 6	DnaJ heat shock protein family (Hsp40) member C30
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GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Exosome (RNase Complex) Nucleoplasm Nucleolus Cytosol	Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Exoribonuclease Activity	Protein Binding
	Biological Process	RRNA Processing RRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' U4 SnRNA 3'-end Processing Regulation Of MRNA Stability Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay DNA Deamination Isotype Switching Positive Regulation Of Isotype Switching Nuclear MRNA Surveillance Polyadenylation-dependent SnoRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 3' to 5' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Blood protein levels ( 29875488)
Interacting Genes		37 interacting genes: C1QBP CHPF DCP1B DIS3 DNAJC30 EIF3I ESRRA EXOSC1 EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC7 EXOSC8 EXOSC9 GSE1 HBS1L LSM1 LSM7 LSM8 MAN2C1 MIF4GD MOCS3 MPHOSPH6 MPP6 MRPL4 MRPS18B MTREX NDUFA13 NUDT21 PSMB1 RAB3GAP2 SRSF3 TUFM UPF2 XRN1 ZFP36	6 interacting genes: APP CREB3 EXOSC6 FBXO7 LMNA S100B
Entrez ID		118460	84277
HPRD ID		12107	10303
Ensembl ID		ENSG00000223496	ENSG00000176410
Uniprot IDs		Q5RKV6	B3KSU4 Q96LL9
PDB IDs		2NN6 6D6Q 6D6R 6H25	2YUA
Enriched GO Terms of Interacting Partners?
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