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ADCYAP1 and ADCYAP1R1
Number of citations of the paper that reports this interaction (PubMedID
10583729
)
27
Data Source:
HPRD
(in vivo, in vitro)
ADCYAP1
ADCYAP1R1
Description
adenylate cyclase activating polypeptide 1
ADCYAP receptor type I
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cell
Neuron Projection
Terminal Bouton
Perikaryon
Cell
Endosome
Rough Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
Bicellular Tight Junction
Cell Surface
Neuron Projection
Intracellular Membrane-bounded Organelle
Receptor Complex
Molecular Function
Signaling Receptor Binding
Neuropeptide Hormone Activity
Protein Binding
Pituitary Adenylate Cyclase Activating Polypeptide Activity
Pituitary Adenylate Cyclase-activating Polypeptide Receptor Binding
Peptide Hormone Receptor Binding
Vasoactive Intestinal Polypeptide Receptor Activity
Protein Binding
Adenylate Cyclase Binding
G Protein-coupled Peptide Receptor Activity
Peptide Hormone Binding
ADP-ribosylation Factor Binding
Signaling Receptor Activity
Neuropeptide Binding
Biological Process
Ovarian Follicle Development
Behavioral Fear Response
Histamine Secretion
Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Adenylate Cyclase Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Neuropeptide Signaling Pathway
Cell-cell Signaling
Female Pregnancy
Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cell Proliferation
Negative Regulation Of Muscle Cell Apoptotic Process
Positive Regulation Of Neuron Projection Development
Sensory Perception Of Pain
CAMP-mediated Signaling
Pituitary Gland Development
Insulin Secretion
Neuron Projection Development
Positive Regulation Of Interleukin-6 Production
Regulation Of Protein Localization
Negative Regulation Of GTPase Activity
Response To Starvation
Negative Regulation Of Potassium Ion Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of CAMP-mediated Signaling
Response To Ethanol
Negative Regulation Of Cell Cycle
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
ATP Metabolic Process
Positive Regulation Of Synaptic Transmission, Glutamatergic
Regulation Of Postsynaptic Membrane Potential
Positive Regulation Of Growth Hormone Secretion
Negative Regulation Of Glial Cell Proliferation
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Oligodendrocyte Progenitor Proliferation
Cellular Response To Glucocorticoid Stimulus
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Somatostatin Secretion
Positive Regulation Of Blood Vessel Diameter
Positive Regulation Of Cold-induced Thermogenesis
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Spermatogenesis
Positive Regulation Of Calcium Ion Transport Into Cytosol
CAMP-mediated Signaling
Cell Differentiation
Response To Estradiol
Multicellular Organismal Response To Stress
Positive Regulation Of CAMP-mediated Signaling
Response To Ethanol
Development Of Primary Female Sexual Characteristics
Positive Regulation Of Small GTPase Mediated Signal Transduction
Negative Regulation Of Cell Death
Positive Regulation Of Inositol Phosphate Biosynthetic Process
Pathways
NGF-independant TRKA activation
G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
NGF-independant TRKA activation
G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Drugs
2,6-Diamino-Hexanoic Acid Amide
Diseases
GWAS
Chronotype (
30696823
)
Midgestational cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Obesity-related traits (
23251661
)
Very long-chain saturated fatty acid levels (fatty acid 22:0) (
25378659
)
Cluster headache (
27957625
)
Major depressive disorder (
21621269
)
Non-word reading (
30741946
)
Vitamin B levels in ischemic stroke (
25147783
)
Interacting Genes
8 interacting genes:
ADCYAP1R1
CASP2
CPAMD8
MME
SCTR
SHH
VIPR1
VIPR2
3 interacting genes:
ADCYAP1
CALM1
TMEM97
Entrez ID
116
117
HPRD ID
02369
00045
Ensembl ID
ENSG00000141433
ENSG00000078549
Uniprot IDs
B7Z222
P18509
A0A090N8F8
P41586
PDB IDs
1GEA
2D2P
2JOD
2JOD
3N94
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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