ECD and TXNIP

Number of citations of the paper that reports this interaction (PubMedID 23880345)
7

Data Source:
BioGRID (affinity chromatography technology, pull down, two hybrid)

		ECD	TXNIP
Description		ecdysoneless cell cycle regulator	thioredoxin interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol
	Molecular Function	Protein Binding Histone Acetyltransferase Binding	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	MRNA Processing Cell Proliferation RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Mechanical Stimulus Response To Glucose Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Proliferation Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell
Pathways			The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: CSNK2A1 EWSR1 NR3C1 PSEN2 TXNIP	18 interacting genes: DDIT4 ECD FHL1 HDAC1 HDAC3 HSPB2 ITCH KPNA2 NLGN3 PRKAA1 PTPN11 SCEL SMURF2 TXN TXNRD1 UBR5 ZBTB16 ZBTB32
Entrez ID		11319	10628
HPRD ID		11032	05964
Ensembl ID		ENSG00000122882	ENSG00000265972
Uniprot IDs		O95905	Q9H3M7
PDB IDs			4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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