DDX20 and SNRPD2

Number of citations of the paper that reports this interaction (PubMedID 10601333)
85

Data Source:
HPRD (in vivo, in vitro)

		DDX20	SNRPD2
Description		DEAD-box helicase 20	small nuclear ribonucleoprotein D2 polypeptide
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Protein Binding, Bridging Histone Deacetylase Binding Repressing Transcription Factor Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process Import Into Nucleus	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Import Into Nucleus
Pathways		snRNP Assembly	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Artenimol
Diseases
GWAS		Body mass index ( 29273807) Metabolite levels ( 23823483)	Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		33 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 LSM2 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53	26 interacting genes: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 PSMD8 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10
Entrez ID		11218	6633
HPRD ID		05859	03038
Ensembl ID		ENSG00000064703	ENSG00000125743
Uniprot IDs		Q9H4N4 Q9UHI6	P62316
PDB IDs		2OXC 3B7G	1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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