SNRPD2 and STXBP2

Number of citations of the paper that reports this interaction (PubMedID 11748230)
54

Data Source:
HPRD (in vitro)

		SNRPD2	STXBP2
Description		small nuclear ribonucleoprotein D2 polypeptide	syntaxin binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Extracellular Region Cytosol Plasma Membrane Apical Plasma Membrane Specific Granule Azurophil Granule Zymogen Granule Membrane Cytolytic Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule
	Molecular Function	RNA Binding Protein Binding	Protein Binding Syntaxin-1 Binding Syntaxin-3 Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Import Into Nucleus	Leukocyte Mediated Cytotoxicity Platelet Degranulation Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation Cellular Response To Interferon-gamma
Pathways		snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Platelet degranulation Other interleukin signaling
Drugs		Artenimol
Diseases
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		26 interacting genes: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 PSMD8 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10	13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		6633	6813
HPRD ID		03038	03423
Ensembl ID		ENSG00000125743	ENSG00000076944
Uniprot IDs		P62316	Q15833 Q53GF4
PDB IDs		1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9	4CCA
Enriched GO Terms of Interacting Partners?
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