TREH and RAB18

		TREH	RAB18
Description		trehalase	RAB18, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Anchored Component Of Membrane Anchored Component Of Plasma Membrane Extracellular Exosome	Intracellular Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Synapse Endoplasmic Reticulum Tubular Network
	Molecular Function	Alpha,alpha-trehalase Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Trehalose Metabolic Process Trehalose Catabolic Process Animal Organ Morphogenesis	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Rab Protein Signal Transduction Lipid Droplet Organization Neutrophil Degranulation Import Into Nucleus Endoplasmic Reticulum Tubular Network Organization
Pathways		Digestion of dietary carbohydrate	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Warburg micro syndrome
GWAS		Celiac disease ( 22057235 25920553) Diffuse cutaneous systemic sclerosis ( 24387989) Height ( 20881960) Hip minimal joint space width ( 27701424) LDL cholesterol ( 30275531) Multiple sclerosis ( 24076602) Non-albumin protein levels ( 29403010) Serum alkaline phosphatase levels ( 31666285) Serum metabolite levels ( 24625756) Systemic sclerosis ( 24387989) Vitiligo ( 22951725)	Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		1 interacting genes: RAB18	13 interacting genes: APBB1IP CHM DVL3 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN
Entrez ID		11181	22931
HPRD ID		02038	03731
Ensembl ID		ENSG00000118094	ENSG00000099246
Uniprot IDs		O43280	A0A087X163 B7Z4P9 B7Z5V3 Q9NP72
PDB IDs			1X3S
Enriched GO Terms of Interacting Partners?
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