RAB32 and CHM

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		RAB32	CHM
Description		RAB32, member RAS oncogene family	CHM Rab escort protein
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Early Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Endomembrane System Membrane Phagocytic Vesicle Membrane Early Endosome Lumen Melanosome Membrane Melanosome Mitochondria-associated ER Membrane Phagocytic Vesicle	Nucleus Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding AP-2 Adaptor Complex Binding AP-1 Adaptor Complex Binding AP-3 Adaptor Complex Binding BLOC-2 Complex Binding	Rab Geranylgeranyltransferase Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Mitochondrion Organization Vesicle-mediated Transport Antigen Processing And Presentation Melanosome Organization Rab Protein Signal Transduction Endosome To Melanosome Transport Protein Localization To Membrane Phagosome Maturation Melanosome Assembly	Protein Targeting To Membrane Small GTPase Mediated Signal Transduction Visual Perception Vesicle-mediated Transport Protein Geranylgeranylation Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Post-translational Protein Modification
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS		Leprosy ( 27976721 25642632 22019778) Metabolite levels ( 23823483)	Metabolite levels ( 23823483) Pit-and-Fissure caries ( 24556642) Smooth-surface caries ( 24556642)
Interacting Genes		2 interacting genes: CHM PRKAR2A	11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A
Entrez ID		10981	1121
HPRD ID		06700	02312
Ensembl ID		ENSG00000118508	ENSG00000188419
Uniprot IDs		Q13637	A8K545 B4DRL9 P24386
PDB IDs		4CYM 4CZ2 5OEC 5OED 6FF8
Enriched GO Terms of Interacting Partners?
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