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NPFFR2 and HCRT
Number of citations of the paper that reports this interaction (PubMedID
12609745
)
0
Data Source:
HPRD
(in vivo)
NPFFR2
HCRT
Description
neuropeptide FF receptor 2
hypocretin neuropeptide precursor
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Actin Cytoskeleton
Extracellular Region
Cell
Rough Endoplasmic Reticulum
Synaptic Vesicle
Cell Junction
Secretory Granule
Perinuclear Region Of Cytoplasm
Postsynapse
Molecular Function
G Protein-coupled Receptor Activity
Neuropeptide Receptor Activity
Opioid Receptor Binding
Peptide Binding
Neuropeptide Hormone Activity
Type 1 Hypocretin Receptor Binding
Type 2 Hypocretin Receptor Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Detection Of Abiotic Stimulus
Cellular Response To Hormone Stimulus
Regulation Of MAPK Cascade
Regulation Of Adenylate Cyclase Activity
Regulation Of CAMP-dependent Protein Kinase Activity
Temperature Homeostasis
G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Chemical Synaptic Transmission
Negative Regulation Of DNA Replication
Sleep
Response To Starvation
Eating Behavior
Negative Regulation Of Potassium Ion Transport
Regulation Of Neurotransmitter Secretion
Positive Regulation Of Calcium Ion Transport
Negative Regulation Of Transmission Of Nerve Impulse
Positive Regulation Of Transmission Of Nerve Impulse
Excitatory Postsynaptic Potential
Positive Regulation Of Cold-induced Thermogenesis
Pathways
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events
Drugs
Pidolic Acid
Diseases
GWAS
Interacting Genes
3 interacting genes:
HCRT
NPFF
NPY
3 interacting genes:
HCRTR1
HCRTR2
NPFFR2
Entrez ID
10886
3060
HPRD ID
16244
03836
Ensembl ID
ENSG00000056291
ENSG00000161610
Uniprot IDs
A0PJM9
Q9Y5X5
O43612
PDB IDs
1CQ0
1R02
1UVQ
1WSO
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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