MXD4 and MLX

Number of citations of the paper that reports this interaction (PubMedID 11230181)
37

Data Source:
HPRD (in vitro, in vivo)

		MXD4	MLX
Description		MAX dimerization protein 4	MAX dimerization protein MLX
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity Protein Binding Protein Dimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Nuclear signaling by ERBB4	ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)
Interacting Genes		6 interacting genes: MAX MLX SHBG SIN3A SMC3 TCP10L	14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32
Entrez ID		10608	6945
HPRD ID		10103	04278
Ensembl ID		ENSG00000123933	ENSG00000108788
Uniprot IDs		Q14582	Q9UH92
PDB IDs
Enriched GO Terms of Interacting Partners?
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