SH2B2 and ASB6

Number of citations of the paper that reports this interaction (PubMedID 15231829)
21

		SH2B2	ASB6
Description		SH2B adaptor protein 2	ankyrin repeat and SOCS box containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Cytosol
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Blood Coagulation Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification
Pathways		Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)
Interacting Genes		22 interacting genes: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN MTDH NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK	5 interacting genes: APP FAM9B L3MBTL3 RNF41 SH2B2
Entrez ID		10603	140459
HPRD ID		16097	10673
Ensembl ID		ENSG00000160999	ENSG00000148331
Uniprot IDs		O14492	F6TX30 Q9NWX5
PDB IDs		1Q2H
Enriched GO Terms of Interacting Partners?
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