SMC2 and TRAF3IP1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		SMC2	TRAF3IP1
Description		structural maintenance of chromosomes 2	TRAF3 interacting protein 1
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GO Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensin Complex Condensin Core Heterodimer Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base
	Molecular Function	Single-stranded DNA Binding Protein Binding ATP Binding	Protein Binding Microtubule Binding
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Protein Complex Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Intraciliary Transport Involved In Cilium Assembly Post-anal Tail Morphogenesis Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways		Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Basal cell carcinoma ( 31174203) Keratinocyte cancer (MTAG) ( 31174203) Orofacial clefts (maternal alcohol consumption interaction) ( 21618603) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Sensorimotor dexterity ( 31596458)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		9 interacting genes: ABCC5 DISC1 DNMT3B ERP44 GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1	28 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		10592	26146
HPRD ID		09277	09571
Ensembl ID		ENSG00000136824	ENSG00000204104
Uniprot IDs		A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1	Q8TDR0
PDB IDs		4U4P	2EQO
Enriched GO Terms of Interacting Partners?
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