CENPA and AURKC

Number of citations of the paper that reports this interaction (PubMedID 20663916)
35

Data Source:
BioGRID (enzymatic study)

		CENPA	AURKC
Description		centromere protein A	aurora kinase C
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nuclear Nucleosome Condensed Chromosome Inner Kinetochore Cell Nucleus Nucleoplasm Cytosol Nuclear Pericentric Heterochromatin	Condensed Nuclear Chromosome, Centromeric Region Condensed Chromosome Cytoplasm Spindle Spindle Microtubule Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Protein Heterodimerization Activity	Protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cytokinesis Viral Process CENP-A Containing Nucleosome Assembly Kinetochore Assembly Protein Localization To Chromosome, Centromeric Region	Protein Phosphorylation Mitotic Spindle Organization Spermatogenesis Attachment Of Spindle Microtubules To Kinetochore Histone Modification Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Histone-serine Phosphorylation Oocyte Development Mitotic Spindle Midzone Assembly Cell Division Meiotic Cell Cycle
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: AURKB AURKC CDKN2A CUL4A DIAPH1 DIAPH2 H3C3 H4C6 HJURP PARP1 PARP2	10 interacting genes: BIRC5 BRCA1 CENPA H3C1 INCENP LNX1 NEDD4 NEDD4L SRPK1 TACC2
Entrez ID		1058	6795
HPRD ID		00313	04605
Ensembl ID		ENSG00000115163	ENSG00000105146
Uniprot IDs		P49450	Q9UQB9
PDB IDs		3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG	6GR8 6GR9
Enriched GO Terms of Interacting Partners?
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