CEL and LTF

Number of citations of the paper that reports this interaction (PubMedID 3995055)
1

Data Source:
HPRD (in vitro)

		CEL	LTF
Description		carboxyl ester lipase	lactotransferrin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Integral Component Of Plasma Membrane Cell Surface Synapse Extracellular Exosome Presynapse	Extracellular Region Extracellular Space Cell Nucleus Cytoplasm Cell Surface Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Extracellular Exosome Phagocytic Vesicle Lumen Tertiary Granule Lumen
	Molecular Function	Catalytic Activity Sterol Esterase Activity Triglyceride Lipase Activity Protein Binding Acetylesterase Activity Heparin Binding Hydrolase Activity Signaling Receptor Activity Neurexin Family Protein Binding	Lipopolysaccharide Binding DNA Binding Serine-type Endopeptidase Activity Cysteine-type Endopeptidase Inhibitor Activity Iron Ion Binding Protein Binding Heparin Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Lipid Metabolic Process Cholesterol Catabolic Process Neuron Cell-cell Adhesion Chemical Synaptic Transmission Fatty Acid Catabolic Process Protein Esterification Pancreatic Juice Secretion Intestinal Cholesterol Absorption Lipid Digestion Intestinal Lipid Catabolic Process Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Postsynaptic Membrane Assembly Presynaptic Membrane Assembly	Ossification Regulation Of Cytokine Production Retina Homeostasis Innate Immune Response In Mucosa Proteolysis Humoral Immune Response Antimicrobial Humoral Response Antibacterial Humoral Response Antifungal Humoral Response Killing Of Cells Of Other Organism Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of ATPase Activity Iron Assimilation By Chelation And Transport Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Cellular Protein Metabolic Process Negative Regulation By Host Of Viral Process Negative Regulation Of Viral Genome Replication Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Viral Process Defense Response To Gram-negative Bacterium Positive Regulation Of NF-kappaB Transcription Factor Activity Membrane Disruption In Other Organism Bone Morphogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Bone Mineralization Involved In Bone Maturation Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Positive Regulation Of Chondrocyte Proliferation Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of Osteoclast Development
Pathways			Mtb iron assimilation by chelation Neutrophil degranulation Metal sequestration by antimicrobial proteins Antimicrobial peptides Amyloid fiber formation
Drugs			3h-Indole-5,6-Diol Lauric Acid Nitrilotriacetic Acid Alpha-D-Fucose Nimesulide 2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE Parecoxib
Diseases		Maturity onset diabetes of the young (MODY)
GWAS		Blood protein levels ( 30072576 29875488) Early-onset Parkinson's disease ( 28256260)	AIDS progression ( 21502085) Blood protein levels ( 30072576 29875488 28240269) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Inflammatory bowel disease ( 26192919) Macular thickness ( 30535121) Ulcerative colitis ( 26192919)
Interacting Genes		3 interacting genes: BPGM LTF OLR1	11 interacting genes: CALM1 CD14 CEL CP EPPIN ITLN1 LCN1 LRP1 LYZ MUC7 UBC
Entrez ID		1056	4057
HPRD ID		07509	01028
Ensembl ID		ENSG00000170835	ENSG00000012223
Uniprot IDs		B4DSX9 O75612 Q86SR3 X6R868	B3KSL2 E7ER44 P02788 Q2TUW9 V9HWI4
PDB IDs			1B0L 1BKA 1CB6 1DSN 1EH3 1FCK 1H43 1H44 1H45 1HSE 1L5T 1LCF 1LCT 1LFG 1LFH 1LFI 1LGB 1N76 1SQY 1U62 1VFD 1VFE 1XV4 1XV7 1Z6V 1Z6W 2BJJ 2DP4 2GMC 2GMD 2HD4 2PMS
Enriched GO Terms of Interacting Partners?
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