DEAF1 and FHL1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		DEAF1	FHL1
Description		DEAF1 transcription factor	four and a half LIM domains 1
Image
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Extracellular Region Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Behavioral Fear Response Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Germ Cell Development Visual Learning Anatomical Structure Morphogenesis Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS
Interacting Genes		19 interacting genes: AIMP2 ASCC2 CDC37 CDKN1A CDKN2A FHL1 GOLGA3 GSK3A GSK3B HRAS INTS1 LMO4 PELI2 PIN1 PPP1CA PPP1CC RAD23B RIDA TK1	21 interacting genes: AKAP12 CBX4 CDC25C CHEK2 DBN1 DEAF1 EED FHL2 HES1 HIVEP3 MYBPC1 PDE4DIP PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE
Entrez ID		10522	2273
HPRD ID		04027	02157
Ensembl ID		ENSG00000177030	ENSG00000022267
Uniprot IDs		O75398	B7Z9A1 Q13642 Q5JXI2
PDB IDs		2JW6 4A24 5UWW	1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?
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