SEC23A and MIA2

Number of citations of the paper that reports this interaction (PubMedID 21525241)
56

Data Source:
BioGRID (two hybrid)

		SEC23A	MIA2
Description		Sec23 homolog A, COPII coat complex component	MIA SH3 domain ER export factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Extrinsic Component Of Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of GTPase Activity COPII Vesicle Coating Protein Localization To Plasma Membrane Cargo Loading Into COPII-coated Vesicle	ER To Golgi Vesicle-mediated Transport Protein Secretion Cargo Loading Into Vesicle
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Cargo concentration in the ER
Drugs
Diseases		Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS		Metabolite levels ( 23823483) Vitamin D levels ( 29343764)
Interacting Genes		11 interacting genes: CDK16 CDK18 DCTN1 GLRA2 MIA2 MIA3 NDRG1 SDCBP2 SEC16A SEC24B SEC24C	13 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PSMA3 RASAL2 SEC23A SEC24C SS18L1 TLE5 TTC23L
Entrez ID		10484	4253
HPRD ID		06714	03680
Ensembl ID		ENSG00000100934	ENSG00000150527
Uniprot IDs		Q15436	Q4G155 Q59FD2 Q96PC5
PDB IDs		2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX 5KYN 5KYU 5KYW 5KYX 5KYY 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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