DENND4A and TLX3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		DENND4A	TLX3
Description		DENN domain containing 4A	T cell leukemia homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nuclear Chromatin Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Respiratory Gaseous Exchange Negative Regulation Of Neuron Differentiation Neuron Fate Specification
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hemoglobin concentration ( 27863252) Intelligence (MTAG) ( 29326435) Logical memory (delayed recall) in normal cognition ( 29274321) Mean corpuscular hemoglobin ( 29403010 20139978 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Red blood cell traits ( 23222517)
Interacting Genes		6 interacting genes: CEBPE CLK1 PCBD1 SERTAD1 TLX3 YWHAG	16 interacting genes: DENND4A GTF2A1L H2BC11 HNRNPUL1 HOPX ING4 IRF9 LMO2 MEIS1 PPP1CC PQBP1 SNTA1 SP1 TLE1 TLE2 ZNF41
Entrez ID		10260	30012
HPRD ID		02662	06868
Ensembl ID		ENSG00000174485	ENSG00000164438
Uniprot IDs		Q05C90 Q7Z401	O43711
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?