PPIF and VDAC1

Number of citations of the paper that reports this interaction (PubMedID 9874241)
103

Data Source:
HPRD (in vitro)

		PPIF	VDAC1
Description		peptidylprolyl isomerase F	voltage dependent anion channel 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Unfolded Protein Binding	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Response To Ischemia Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Behavioral Fear Response Pyruvate Metabolic Process Anion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Inorganic Anion Transport Viral Process Macroautophagy Epithelial Cell Differentiation Anion Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport
Drugs		Cyclosporine L-Proline 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane 7-AMINO-4-METHYL-CHROMEN-2-ONE	Aluminium monostearate
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Metabolite levels ( 23823483)	Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		6 interacting genes: ABI2 BANP CMTM5 SERPINB5 SLC25A4 VDAC1	22 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE PRKN RAF1 RNF31 SUMO4 TOMM20 TUBA4A
Entrez ID		10105	7416
HPRD ID		06839	05137
Ensembl ID		ENSG00000108179	ENSG00000213585
Uniprot IDs		A0A024QZS4 P30405	A0A1L1UHR1 B3KTS5 P21796
PDB IDs		2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 5NWO 6GJX 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1	2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73
Enriched GO Terms of Interacting Partners?
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