ARPC4 and ARPC1B

Number of citations of the paper that reports this interaction (PubMedID 11721045)
173

Data Source:
HPRD (in vitro)

		ARPC4	ARPC1B
Description		actin related protein 2/3 complex subunit 4	actin related protein 2/3 complex subunit 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Site Of Double-strand Break Cell Projection Extracellular Exosome	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Tubulobulbar Complex Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Binding, Bridging Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding
	Biological Process	Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Actin Nucleation Ephrin Receptor Signaling Pathway Membrane Organization	Response To Estradiol Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Response To Estrogen Ephrin Receptor Signaling Pathway
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS			Alcohol consumption ( 31358974) Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		11 interacting genes: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L CLK1 NELFCD PNMA5 RNF130	11 interacting genes: ACTB ACTR2 APP ARPC2 ARPC4 ARPC5 AURKA PAK1 PMPCB SRPK2 WAS
Entrez ID		10093	10095
HPRD ID		10368	10366
Ensembl ID		ENSG00000241553	ENSG00000130429
Uniprot IDs		P59998	A4D275 O15143
PDB IDs
Enriched GO Terms of Interacting Partners?
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