PROS1

Description		protein S
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Golgi Lumen Plasma Membrane Platelet Alpha Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Endopeptidase Inhibitor Activity Calcium Ion Binding
	Biological Process	Platelet Degranulation ER To Golgi Vesicle-mediated Transport Blood Coagulation Negative Regulation Of Endopeptidase Activity Regulation Of Complement Activation Fibrinolysis Leukocyte Migration
Pathways		Platelet degranulation Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Gamma-carboxylation of protein precursors Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Removal of aminoterminal propeptides from gamma-carboxylated proteins Cell surface interactions at the vascular wall Regulation of Complement cascade
Drugs		Drotrecogin alfa Menadione Sodium Tetradecyl Sulfate
Diseases		Inherited thrombophilia
GWAS		Systemic lupus erythematosus ( 28714469)
Interacting Genes		10 interacting genes: C4BPA C4BPB F10 F2 F5 F8 PROC RPSA TBK1 TYRO3
Entrez ID		5627
HPRD ID		01473
Ensembl ID		ENSG00000184500
Uniprot IDs		A0A0S2Z4K3 A0A0S2Z4L3 P07225
PDB IDs		1Z6C
Enriched GO Terms of Interacting Partners?
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