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MYBL2

Description MYB proto-oncogene like 2
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Myb Complex
Molecular Function
  • RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Factor Activity
  • Protein Binding
Biological Process
  • Mitotic Cell Cycle
  • Regulation Of Transcription By RNA Polymerase II
  • Positive Regulation Of Neuron Apoptotic Process
  • Positive Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Cell Cycle
  • Mitotic Spindle Assembly
  • Cellular Response To Leukemia Inhibitory Factor
Pathways
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • Polo-like kinase mediated events
  • TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS
Interacting Genes 31 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN52 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBBP4 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622
Entrez ID 4605
HPRD ID 03247
Ensembl ID ENSG00000101057
Uniprot IDs P10244
PDB IDs 6C48
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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