IL37

Description		interleukin 37
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding
	Biological Process	Inflammatory Response To Antigenic Stimulus Inflammatory Response Immune Response Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Interleukin-6 Biosynthetic Process Regulation Of Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Cytokine Stimulus Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Tumor Necrosis Factor Secretion
Pathways		Interleukin-37 signaling Interleukin-18 signaling
Drugs
Diseases
GWAS		Dysmenorrheic pain severity ( 29855537) Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Pulmonary function ( 23932459) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) ( 24554482)
Interacting Genes		5 interacting genes: CASP1 CASP4 IL18BP IL18R1 SMAD3
Entrez ID		27178
HPRD ID		05695
Ensembl ID		ENSG00000125571
Uniprot IDs		Q9NZH6
PDB IDs		5HN1 6NCU
Enriched GO Terms of Interacting Partners?
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