FGF21

Description		fibroblast growth factor 21
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Positive Regulation Of Triglyceride Catabolic Process Regulation Of Low-density Lipoprotein Particle Clearance Response To Activity Endoplasmic Reticulum Unfolded Protein Response Response To Nutrient Levels Cellular Response To Drug Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Glucose Stimulus Cellular Response To Glucagon Stimulus Cellular Response To Low-density Lipoprotein Particle Stimulus Endothelial Cell Apoptotic Process Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Neuron Death Response To Methionine Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Cellular hexose transport Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Dietary macronutrient intake ( 23372041 23636237 29988085) Resting metabolic rate ( 28476931) Retinal vascular caliber ( 21060863) Triglycerides ( 30275531) Urinary sodium excretion ( 31409800)
Interacting Genes		6 interacting genes: CDC25A CDH7 KLB MAPK7 NEDD4 TNS2
Entrez ID		26291
HPRD ID		09447
Ensembl ID		ENSG00000105550
Uniprot IDs		Q9NSA1
PDB IDs		5VAQ
Enriched GO Terms of Interacting Partners?
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