TARS3 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
Novel	ARRDC4	arrestin domain containing 4
Novel	DNM1P46	dynamin 1 pseudogene 46
Novel	LRRC28	leucine rich repeat containing 28
Novel	SELENOS	selenoprotein S	E3 ubiquitin ligases ubiquitinate target proteins
Novel	TM2D3	TM2 domain containing 3
	ARPC3	actin related protein 2/3 complex subunit 3	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
	ATF4	activating transcription factor 4	ATF4 activates genes in response to endoplasmic reticulum stress ATF4 activates genes in response to endoplasmic reticulum stress PERK regulates gene expression ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency Response of EIF2AK1 (HRI) to heme deficiency NFE2L2 regulating anti-oxidant/detoxification enzymes NFE2L2 regulating ER-stress associated genes	Pseudoephedrine
	DSCAM	DS cell adhesion molecule	DSCAM interactions DSCAM interactions
	ECSIT	ECSIT signaling integrator	MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
	LGALS14	galectin 14
	RNF10	ring finger protein 10
	TARS2	threonyl-tRNA synthetase 2, mitochondrial	Mitochondrial tRNA aminoacylation	Threonine

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