TARS3 and TM2D3

		TARS3	TM2D3
Description		threonyl-tRNA synthetase 3	TM2 domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Aminoacyl-tRNA Ligase Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Threonyl-tRNA Aminoacylation TRNA Aminoacylation	Positive Regulation Of Notch Signaling Pathway Lateral Inhibition
Pathways
Drugs
Diseases
GWAS			Depression in multiple sclerosis (pre-diagnosis) ( 33296963) Triglyceride levels ( 32154731)
Interacting Genes		7 interacting genes: ARPC3 ATF4 DSCAM ECSIT LGALS14 RNF10 TARS2	3 interacting genes: ERRFI1 LCOR PAXIP1
Entrez ID		123283	80213
HPRD ID		15469	16554
Ensembl ID		ENSG00000185418	ENSG00000184277
Uniprot IDs		A2RTX5	B4DLL2 E7EPS7 H0YNS4 Q9BRN9
PDB IDs
Enriched GO Terms of Interacting Partners?			Ubiquitin-specific Protease Binding Adipose Tissue Development Connective Tissue Development Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Cellular Response To Lipid Response To Estradiol Cellular Response To Insulin Stimulus Uterine Epithelium Development Response To 1-oleoyl-sn-glycerol 3-phosphate Derlin-1-VIMP Complex Intracellular Signal Transduction Chorion Development Negative Regulation Of Protein Autophosphorylation Anatomical Structure Homeostasis Tissue Homeostasis Cellular Response To Peptide Hormone Stimulus Oviduct Epithelium Development Regulation Of Tumor Necrosis Factor Production Response To Insulin Threonine-tRNA Ligase Activity Threonyl-tRNA Aminoacylation Response To Lipid Limb Joint Morphogenesis Cellular Response To Oxygen-containing Compound Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Macrophage Apoptotic Process Osteoclast Development MLL3/4 Complex Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Isotype Switching To IgG Isotypes Chondrocyte Proliferation Negative Regulation Of Collagen Biosynthetic Process Skin Morphogenesis Negative Regulation Of Signaling Receptor Activity Lung Vasculature Development Negative Regulation Of Cytokine Production Response To Peptide Hormone Fat Pad Development Progesterone Receptor Signaling Pathway Regulation Of Type B Pancreatic Cell Proliferation Lung Epithelium Development Cellular Response To Chemical Stress Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Cellular Response To Hormone Stimulus ER Overload Response Negative Regulation Of Acute Inflammatory Response
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