Search Results for: RAG2

7 interactions involving RAG2 - recombination activating 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel CAPRIN1 cell cycle associated protein 1
Novel LMO2 LIM domain only 2
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
Novel RCN1 reticulocalbin 1
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
FOXP1 forkhead box P1
IPO5 importin 5
  • vRNP Assembly
RAG1 recombination activating 1
  • Interleukin-7 signaling
  • MAPK6/MAPK4 signaling
  • Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
  • T-B-Severe combined immunodeficiencies (SCIDs), including the following four diseases: Adenosine deaminase (ADA) deficiency; Recombinase activating gene (RAG) deficiencies; Artemis deficiency; Reticular dysgenesis
SKP2 S-phase kinase associated protein 2
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • SCF(Skp2)-mediated degradation of p27/p21
  • Ub-specific processing proteases
  • Orc1 removal from chromatin
  • Cyclin D associated events in G1
  • Regulation of RUNX2 expression and activity
  • Neddylation
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
  • Regulation of BACH1 activity
  • Antigen processing: Ubiquitination & Proteasome degradation

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