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Novel |
ATG16L1 |
autophagy related 16 like 1 |
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Novel |
CIC |
capicua transcriptional repressor |
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Novel |
VRK2 |
VRK serine/threonine kinase 2 |
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RHOD GTPase cycle
- RHOG GTPase cycle
- RAC3 GTPase cycle
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ANXA7 |
annexin A7 |
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BCL2L1 |
BCL2 like 1 |
- BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
- Interleukin-4 and Interleukin-13 signaling
- The NLRP1 inflammasome
- RAS processing
- SARS-CoV-1-mediated effects on programmed cell death
- STAT5 activation downstream of FLT3 ITD mutants
- NFE2L2 regulating tumorigenic genes
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- 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
- Gossypol
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CNIH3 |
cornichon family AMPA receptor auxiliary protein 3 |
- COPII-mediated vesicle transport
- Cargo concentration in the ER
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GPR35 |
G protein-coupled receptor 35 |
- Class A/1 (Rhodopsin-like receptors)
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- Furosemide
- Pyrantel
- Kynurenic Acid
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HGS |
hepatocyte growth factor-regulated tyrosine kinase substrate |
- EGFR downregulation
- Lysosome Vesicle Biogenesis
- Ub-specific processing proteases
- Negative regulation of MET activity
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- InlB-mediated entry of Listeria monocytogenes into host cell
- RHOU GTPase cycle
- Endosomal Sorting Complex Required For Transport (ESCRT)
- Inhibition of membrane repair
- Prevention of phagosomal-lysosomal fusion
- RHOBTB3 ATPase cycle
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NFKB1 |
nuclear factor kappa B subunit 1 |
- Activation of NF-kappaB in B cells
- RIP-mediated NFkB activation via ZBP1
- Regulated proteolysis of p75NTR
- Downstream TCR signaling
- NF-kB is activated and signals survival
- Senescence-Associated Secretory Phenotype (SASP)
- FCERI mediated NF-kB activation
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production
- PKMTs methylate histone lysines
- Transcriptional regulation of white adipocyte differentiation
- TAK1-dependent IKK and NF-kappa-B activation
- Interleukin-1 processing
- IkBA variant leads to EDA-ID
- CLEC7A (Dectin-1) signaling
- CD209 (DC-SIGN) signaling
- CLEC7A/inflammasome pathway
- MAP3K8 (TPL2)-dependent MAPK1/3 activation
- Neutrophil degranulation
- The NLRP3 inflammasome
- Transcriptional Regulation by VENTX
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- HCMV Early Events
- Purinergic signaling in leishmaniasis infection
- SARS-CoV-1 activates/modulates innate immune responses
- Regulation of NFE2L2 gene expression
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Regulation of PD-L1(CD274) transcription
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- Sulfasalazine
- Donepezil
- Pseudoephedrine
- Pranlukast
- Pranlukast
- HE3286
- P54
- NOX-700
- SGN-30
- Custirsen
- NF-kappaB Decoy
- Andrographolide
- Triflusal
- Terpinen-4-ol
- Glycyrrhizic acid
- Fish oil
- SC-236
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OGT |
O-linked N-acetylglucosamine (GlcNAc) transferase |
- HATs acetylate histones
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- UCH proteinases
- Formation of WDR5-containing histone-modifying complexes
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OPRM1 |
opioid receptor mu 1 |
- Opioid Signalling
- G-protein activation
- Peptide ligand-binding receptors
- G alpha (i) signalling events
- Interleukin-4 and Interleukin-13 signaling
- MECP2 regulates neuronal receptors and channels
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- Tramadol
- Morphine
- Codeine
- Amitriptyline
- Hydromorphone
- Methadone
- Meperidine
- Oxycodone
- Levallorphan
- Dextromethorphan
- Butorphanol
- Dextropropoxyphene
- Pentazocine
- Naltrexone
- Sufentanil
- Alfentanil
- Fentanyl
- Loperamide
- Nalbuphine
- Levorphanol
- Remifentanil
- Ondansetron
- Anileridine
- Buprenorphine
- Hydrocodone
- Diphenoxylate
- Naloxone
- Oxymorphone
- Dezocine
- Ketamine
- Levacetylmethadol
- Aripiprazole
- Methadyl acetate
- 3-Methylthiofentanyl
- Dimethylthiambutene
- Diamorphine
- Ethylmorphine
- Etorphine
- Carfentanil
- Diprenorphine
- Dihydromorphine
- 3-Methylfentanyl
- V1003
- Epicept NP-1
- LI-301
- Tapentadol
- Nalmefene
- Alvimopan
- Amisulpride
- Morphine glucuronide
- Ketobemidone
- Methylnaltrexone
- Naloxegol
- Cannabidiol
- Trimebutine
- Butyrfentanyl
- Pholcodine
- Eluxadoline
- Tianeptine
- Opium
- Pentoxyverine
- Naldemedine
- Samidorphan
- Metenkefalin
- Medical Cannabis
- Nabiximols
- Loxicodegol
- Oliceridine
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SMCO4 |
single-pass membrane protein with coiled-coil domains 4 |
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SOX4 |
SRY-box transcription factor 4 |
- Deactivation of the beta-catenin transactivating complex
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SPP1 |
secreted phosphoprotein 1 |
- Degradation of the extracellular matrix
- Signaling by PDGF
- Integrin cell surface interactions
- Integrin cell surface interactions
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- RUNX3 Regulates Immune Response and Cell Migration
- Post-translational protein phosphorylation
- Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
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STK11 |
serine/threonine kinase 11 |
- AMPK inhibits chREBP transcriptional activation activity
- Energy dependent regulation of mTOR by LKB1-AMPK
- Regulation of TP53 Activity through Phosphorylation
- FOXO-mediated transcription of cell death genes
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- Peutz-Jeghers syndrome
- Pancreatic cancer
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TK1 |
thymidine kinase 1 |
- G1/S-Specific Transcription
- Pyrimidine salvage
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- Dithioerythritol
- Thymidine 5'-triphosphate
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