| Novel |
COMMD10
|
COMM domain containing 10 |
|
|
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| Novel |
DTWD2
|
DTW motif tRNA-uridine aminocarboxypropyltransferase 2 |
|
|
|
| Novel |
FAM170A
|
family with sequence similarity 170 member A |
|
|
|
| Novel |
PRR16
|
proline rich 16 |
|
|
|
| Novel |
SEMA6A
|
semaphorin 6A |
- Other semaphorin interactions
|
|
|
| Novel |
SRFBP1
|
serum response factor binding protein 1 |
|
|
|
| Novel |
TICAM2
|
TIR domain containing adaptor molecule 2 |
- Caspase activation via Death Receptors in the presence of ligand
- Toll Like Receptor 4 (TLR4) Cascade
- MyD88-independent TLR4 cascade
- TRIF-mediated programmed cell death
- Neutrophil degranulation
- Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
- IKK complex recruitment mediated by RIP1
- TRAF6-mediated induction of TAK1 complex within TLR4 complex
- IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
- Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
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|
|
| Novel |
TNFAIP8
|
TNF alpha induced protein 8 |
|
|
|
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IFIT3
|
interferon induced protein with tetratricopeptide repeats 3 |
- Interferon alpha/beta signaling
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LMNA
|
lamin A/C |
- XBP1(S) activates chaperone genes
- Signaling by BRAF and RAF1 fusions
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- Mandibuloacral dysplasia
- Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
- Emery-Dreifuss muscular dystrophy
- Dilated cardiomyopathy (DCM)
- Limb-girdle muscular dystrophy (LGMD)
- Hutchinson-Gilford progeria syndrome
- Restrictive dermopathy
- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
- Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
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