LVRN and PRR16

		LVRN	PRR16
Description		laeverin	proline rich 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane
	Molecular Function	Aminopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity	Protein Binding
	Biological Process	Proteolysis Peptide Catabolic Process	Positive Regulation Of Translation Positive Regulation Of Cell Size
Pathways
Drugs
Diseases
GWAS		Spontaneous preterm birth without premature rupture of membranes ( 31194736)	Adult body size ( 32376654) Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Body mass index (change over time) ( 25133637) Bronchopulmonary dysplasia ( 23897914) Cognitive decline rate in late mild cognitive impairment ( 26252872) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) Loneliness (linear analysis) ( 27629369) Numerical cognitive ability ( 31620175) Pulse pressure ( 30224653) Verbal cognitive ability ( 31620175) Verbal declarative memory ( 25648963) Weight ( 28552196)
Interacting Genes		2 interacting genes: IFIT3 LMNA	11 interacting genes: ABI2 APP DAPK1 DLG4 NCK2 NEDD4 NEDD4L NOD2 PPP1CA PPP1CC SMURF1
Entrez ID		206338	51334
HPRD ID		07118	14239
Ensembl ID		ENSG00000172901	ENSG00000184838
Uniprot IDs		Q6Q4G3	Q569H4
PDB IDs
Enriched GO Terms of Interacting Partners?			Dendritic Spine Receptor Catabolic Process Positive Regulation Of Catabolic Process Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Projection Organization Protein Modification Process Protein-containing Complex Binding Positive Regulation Of Cellular Component Organization Receptor Metabolic Process NMDA Selective Glutamate Receptor Signaling Pathway Negative Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Protein Metabolic Process PTW/PP1 Phosphatase Complex Sodium Channel Inhibitor Activity Presynapse Postsynapse Potassium Channel Inhibitor Activity Regulation Of Translational Initiation In Response To Stress Glutamatergic Synapse Regulation Of Potassium Ion Export Across Plasma Membrane Protein Polyubiquitination Acetylcholine Receptor Binding Regulation Of Synapse Organization Cell Projection Organization Negative Regulation Of Sodium Ion Transport Regulation Of Cellular Component Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Response To Light Stimulus Response To Metal Ion Response To Lead Ion Transition Metal Ion Binding Positive Regulation Of Dendrite Extension Negative Regulation Of Potassium Ion Transmembrane Transport Regulation Of Translation In Response To Stress Cytoskeletal Anchor Activity Macromolecule Metabolic Process Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Apoptotic Signaling Pathway Protein Phosphatase 1 Binding Regulation Of Translation Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuron Projection Development Photoperiodism Entrainment Of Circadian Clock Ionotropic Glutamate Receptor Signaling Pathway Plasma Membrane Bounded Cell Projection Organization Regulation Of Membrane Potential Positive Regulation Of Supramolecular Fiber Organization Response To Radiation
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