| Novel |
BRS3
|
bombesin receptor subtype 3 |
- Peptide ligand-binding receptors
- G alpha (q) signalling events
|
|
|
| Novel |
HCK
|
HCK proto-oncogene, Src family tyrosine kinase |
- Nef and signal transduction
- FCGR activation
- Regulation of signaling by CBL
- Regulation of signaling by CBL
- FCGR3A-mediated IL10 synthesis
- FCGR3A-mediated phagocytosis
- Signaling by CSF3 (G-CSF)
- Signaling by CSF3 (G-CSF)
- Signaling by CSF1 (M-CSF) in myeloid cells
- Inactivation of CSF3 (G-CSF) signaling
- Inactivation of CSF3 (G-CSF) signaling
- FLT3 signaling through SRC family kinases
|
- 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
- Phosphonotyrosine
- Quercetin
- Bosutinib
- Fostamatinib
|
|
| Novel |
HOPX
|
HOP homeobox |
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
|
|
|
| Novel |
MRPS5
|
mitochondrial ribosomal protein S5 |
- Mitochondrial translation initiation
- Mitochondrial translation elongation
- Mitochondrial translation elongation
- Mitochondrial translation termination
- Mitochondrial ribosome-associated quality control
|
|
|
| Novel |
ZNF43
|
zinc finger protein 43 |
- Generic Transcription Pathway
|
|
|
|
ACE
|
angiotensin I converting enzyme |
- Metabolism of Angiotensinogen to Angiotensins
|
- Ramipril
- Fosinopril
- Trandolapril
- Benazepril
- Enalapril
- Candoxatril
- Moexipril
- Lisinopril
- Perindopril
- Quinapril
- Omapatrilat
- Rescinnamine
- Captopril
- Cilazapril
- Spirapril
- Epicaptopril
- N-acetyl-alpha-D-glucosamine
- Temocapril
- Enalaprilat
- Zofenopril
- Cilazaprilat
|
- Allograft rejection
- Renal tubular dysgenesis
|
|
AQP7
|
aquaporin 7 |
- Transport of glycerol from adipocytes to the liver by Aquaporins
- Passive transport by Aquaporins
|
|
|
|
AVPR2
|
arginine vasopressin receptor 2 |
- Vasopressin-like receptors
- G alpha (s) signalling events
- Vasopressin regulates renal water homeostasis via Aquaporins
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)
|
- Desmopressin
- Vasopressin
- Demeclocycline
- Conivaptan
- Terlipressin
- M0002
- OPC-51803
- Tolvaptan
- Atosiban
- Lypressin
- Pecavaptan
|
- Congenital nephrogenic diabetes insipidus (NDI)
|
|
BEST2
|
bestrophin 2 |
|
|
|
|
CCL4L2
|
C-C motif chemokine ligand 4 like 2 |
- G alpha (i) signalling events
|
|
|
|
CDC27
|
cell division cycle 27 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
CDC42
|
cell division cycle 42 |
- GPVI-mediated activation cascade
- EGFR downregulation
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- CD28 dependent Vav1 pathway
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- DCC mediated attractive signaling
- Inactivation of CDC42 and RAC1
- VEGFA-VEGFR2 Pathway
- Myogenesis
- Myogenesis
- RHO GTPases activate KTN1
- RHO GTPases activate IQGAPs
- RHO GTPases activate PAKs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate Formins
- RHO GTPases Activate Formins
- MAPK6/MAPK4 signaling
- Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
- G beta:gamma signalling through CDC42
- CDC42 GTPase cycle
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RHOQ GTPase cycle
- RHOG GTPase cycle
- RHOJ GTPase cycle
- RHOU GTPase cycle
- RAC3 GTPase cycle
- RHOV GTPase cycle
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
- Factors involved in megakaryocyte development and platelet production
|
- Aminophosphonic acid-guanylate ester
- Guanosine-5'-Diphosphate
|
|
|
CNR2
|
cannabinoid receptor 2 |
- Class A/1 (Rhodopsin-like receptors)
- G alpha (i) signalling events
|
- Dronabinol
- Nabilone
- Ricinoleic acid
- Lasofoxifene
- Cannabidiol
- Tetrahydrocannabivarin
- Medical Cannabis
- Nabiximols
- S-777469
|
|
|
CREB3L1
|
cAMP responsive element binding protein 3 like 1 |
- CREB3 factors activate genes
|
|
|
|
EMD
|
emerin |
- Nuclear Envelope Breakdown
- Initiation of Nuclear Envelope (NE) Reformation
- Depolymerization of the Nuclear Lamina
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RHOD GTPase cycle
- RHOG GTPase cycle
- RAC3 GTPase cycle
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
|
|
- Emery-Dreifuss muscular dystrophy
|
|
FAM209A
|
family with sequence similarity 209 member A |
|
|
|
|
FFAR3
|
free fatty acid receptor 3 |
- G alpha (q) signalling events
- Free fatty acid receptors
|
|
|
|
FXR2
|
FMR1 autosomal homolog 2 |
|
|
|
|
GET1
|
guided entry of tail-anchored proteins factor 1 |
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
|
|
|
|
GJB1
|
gap junction protein beta 1 |
- Oligomerization of connexins into connexons
- Oligomerization of connexins into connexons
- Transport of connexins along the secretory pathway
- Gap junction assembly
|
|
- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
|