CLU - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	ADGRF4	adhesion G protein-coupled receptor F4
Novel	CBR3	carbonyl reductase 3	Phase I - Functionalization of compounds
Novel	DUSP13B	dual specificity phosphatase 13B
Novel	GEMIN7	gem nuclear organelle associated protein 7	snRNP Assembly SARS-CoV-2 modulates host translation machinery
Novel	KRT12	keratin 12	Keratinization Formation of the cornified envelope	Griseofulvin Anthralin	Meesmann corneal dystrophy
Novel	NAT2	N-acetyltransferase 2	Acetylation Paracetamol ADME
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1-dependent IKK and NF-kappa-B activation The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Gantenerumab Aducanumab Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form Lecanemab	Alzheimer's disease (AD)
	BAG6	BAG cochaperone 6	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
	BTG3	BTG anti-proliferation factor 3
	C7	complement C7	Terminal pathway of complement Regulation of Complement cascade		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	C8B	complement C8 beta chain	Terminal pathway of complement Regulation of Complement cascade	Zinc Copper Zinc acetate	Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	C9	complement C9	Terminal pathway of complement Regulation of Complement cascade	Copper	Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	CBY1	chibby 1, beta catenin antagonist	Deactivation of the beta-catenin transactivating complex
	CD209	CD209 molecule	CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions RSV-host interactions
	CLUAP1	clusterin associated protein 1	Intraflagellar transport Intraflagellar transport
	CYP2E1	cytochrome P450 family 2 subfamily E member 1	Xenobiotics CYP2E1 reactions Biosynthesis of maresin-like SPMs Aspirin ADME Paracetamol ADME	Diacerein
	DISC1	DISC1 scaffold protein
	DLG4	discs large MAGUK scaffold protein 4	Signaling by ERBB4 Trafficking of AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor NrCAM interactions Activation of Ca-permeable Kainate Receptor RHO GTPases activate CIT RAF/MAP kinase cascade LGI-ADAM interactions Neurexins and neuroligins Neurexins and neuroligins Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation	Guanidine Guanosine-5'-Monophosphate
	DSCAM	DS cell adhesion molecule	DSCAM interactions DSCAM interactions
	DSCR9	Down syndrome critical region 9

Search Results for: CLU