FXR1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
LZTS2	leucine zipper tumor suppressor 2
MAD1L1	mitotic arrest deficient 1 like 1	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
MAGED1	MAGE family member D1	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
MAGOH	mago homolog, exon junction complex subunit	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
MAGOHB	mago homolog B, exon junction complex subunit	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
MAPK7	mitogen-activated protein kinase 7	ERK/MAPK targets ERK/MAPK targets Signalling to ERK5 Signalling to ERK5 ERKs are inactivated Senescence-Associated Secretory Phenotype (SASP) Gastrin-CREB signalling pathway via PKC and MAPK RET signaling	Acetylsalicylic acid Minocycline Colforsin Fostamatinib
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3
MAPKBP1	mitogen-activated protein kinase binding protein 1
MBIP	MAP3K12 binding inhibitory protein 1	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
MCRS1	microspherule protein 1	HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER Formation of WDR5-containing histone-modifying complexes
MFAP1	microfibril associated protein 1	mRNA Splicing - Major Pathway
MLLT1	MLLT1 super elongation complex subunit	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
MOAP1	modulator of apoptosis 1
MSANTD3	Myb/SANT DNA binding domain containing 3
MTUS2	microtubule associated scaffold protein 2
MVP	major vault protein	Neutrophil degranulation
MX1	MX dynamin like GTPase 1	ISG15 antiviral mechanism Interferon alpha/beta signaling
MYH10	myosin heavy chain 10	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
MYH9	myosin heavy chain 9	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea CD163 mediating an anti-inflammatory response FCGR3A-mediated phagocytosis Signaling by ALK fusions and activated point mutants	Artenimol	MYH9-related kidney diseases, including: Epstein syndrome; Fechtner syndrome Macrothrombocytopenia; May-Hegglin anomaly; Sebastian syndrome; Fechtner syndrome; Epstein syndrome Deafness, autosomal dominant
MYO5B	myosin VB	Vasopressin regulates renal water homeostasis via Aquaporins

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