Search Results for: XPO1

94 interactions involving XPO1 - exportin 1 found:

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Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
NXF3 nuclear RNA export factor 3
NXT1 nuclear transport factor 2 like export factor 1
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
  • HATs acetylate histones
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • UCH proteinases
  • Formation of WDR5-containing histone-modifying complexes
ORC1 origin recognition complex subunit 1
  • E2F-enabled inhibition of pre-replication complex formation
  • Activation of ATR in response to replication stress
  • Assembly of the ORC complex at the origin of replication
  • CDC6 association with the ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • G1/S-Specific Transcription
  • Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
PHAX phosphorylated adaptor for RNA export
  • snRNP Assembly
  • RNA polymerase II transcribes snRNA genes
PHB1 prohibitin 1
  • RAF activation
  • Signaling by moderate kinase activity BRAF mutants
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Processing of SMDT1
  • Signaling downstream of RAS mutants
  • Rocaglamide
  • Didesmethylrocaglamide
PKIA cAMP-dependent protein kinase inhibitor alpha
  • 3,5-Diiodotyrosine
  • Hydroxyfasudil
  • (2S)-1-(3H-Indol-3-yl)-3-{[5-(6-isoquinolinyl)-3-pyridinyl]oxy}-2-propanamine
  • (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE
  • (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
  • (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE
  • N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
  • (S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
  • 6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE
  • (2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
  • (2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
  • 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
  • (2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE
  • (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
  • ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
  • H-89
  • 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
  • N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE
  • 2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE
  • (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
  • 3-pyridin-4-yl-1H-indazole
  • 5-benzyl-1,3-thiazol-2-amine
  • 1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
  • 1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
  • 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium
  • Fasudil
  • Myristic acid
  • A-674563
  • 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE
  • Y-27632
RAD51 RAD51 recombinase
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Homologous DNA Pairing and Strand Exchange
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Transcriptional Regulation by E2F6
  • Meiotic recombination
  • Meiotic recombination
  • Defective homologous recombination repair (HRR) due to BRCA1 loss of function
  • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
  • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
  • Impaired BRCA2 binding to RAD51
  • Impaired BRCA2 binding to PALB2
  • Phosphoaminophosphonic Acid-Adenylate Ester
  • Amuvatinib
RAN RAN, member RAS oncogene family
  • Rev-mediated nuclear export of HIV RNA
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
  • NEP/NS2 Interacts with the Cellular Export Machinery
  • Nuclear import of Rev protein
  • MicroRNA (miRNA) biogenesis
  • Transcriptional regulation by small RNAs
  • tRNA processing in the nucleus
  • Postmitotic nuclear pore complex (NPC) reformation
  • Postmitotic nuclear pore complex (NPC) reformation
  • Guanosine-5'-Diphosphate
RANBP2 RAN binding protein 2
  • ISG15 antiviral mechanism
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Transport of the SLBP independent Mature mRNA
  • Transport of the SLBP Dependant Mature mRNA
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Rev-mediated nuclear export of HIV RNA
  • Transport of Ribonucleoproteins into the Host Nucleus
  • NS1 Mediated Effects on Host Pathways
  • Viral Messenger RNA Synthesis
  • NEP/NS2 Interacts with the Cellular Export Machinery
  • Regulation of Glucokinase by Glucokinase Regulatory Protein
  • Nuclear import of Rev protein
  • Vpr-mediated nuclear import of PICs
  • IPs transport between nucleus and cytosol
  • IP3 and IP4 transport between cytosol and nucleus
  • IP6 and IP7 transport between cytosol and nucleus
  • snRNP Assembly
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of ubiquitinylation proteins
  • Nuclear Pore Complex (NPC) Disassembly
  • Regulation of HSF1-mediated heat shock response
  • SUMOylation of SUMOylation proteins
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA replication proteins
  • Transcriptional regulation by small RNAs
  • Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
  • RHO GTPases Activate Formins
  • tRNA processing in the nucleus
  • Mitotic Prometaphase
  • HCMV Early Events
  • HCMV Late Events
  • EML4 and NUDC in mitotic spindle formation
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • Signaling by ALK fusions and activated point mutants
RANBP3 RAN binding protein 3
RCC1 regulator of chromosome condensation 1
  • Rev-mediated nuclear export of HIV RNA
  • Nuclear import of Rev protein
  • Postmitotic nuclear pore complex (NPC) reformation
RCN2 reticulocalbin 2
RGS14 regulator of G protein signaling 14
  • G alpha (i) signalling events
  • G alpha (i) signalling events
RIC8A RIC8 guanine nucleotide exchange factor A
RPS6KB1 ribosomal protein S6 kinase B1
  • mTORC1-mediated signalling
SERPINB1 serpin family B member 1
  • Neutrophil degranulation
  • CASP4 inflammasome assembly
SERTAD2 SERTA domain containing 2
SIRT2 sirtuin 2
  • Initiation of Nuclear Envelope (NE) Reformation
  • Cambinol
SMAD1 SMAD family member 1
  • Signaling by BMP
  • Ub-specific processing proteases
  • RUNX2 regulates bone development
  • Cardiogenesis
  • Transcriptional regulation of brown and beige adipocyte differentiation by EBF2

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