NUP62 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
IFT20	intraflagellar transport 20	Intraflagellar transport Intraflagellar transport
IFT25	intraflagellar transport 25	Intraflagellar transport Intraflagellar transport		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
IK	IK cytokine	mRNA Splicing - Major Pathway
IKBIP	IKBKB interacting protein	Regulation of NF-kappa B signaling
IPO5	importin 5	vRNP Assembly
ISCU	iron-sulfur cluster assembly enzyme	Maturation of replicase proteins
KANSL1	KAT8 regulatory NSL complex subunit 1	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
KIFC3	kinesin family member C3
KLHL32	kelch like family member 32
KPNA1	karyopherin subunit alpha 1	ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Integration of provirus Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Vpr-mediated nuclear import of PICs Assembly of the ORC complex at the origin of replication Interferon alpha/beta signaling Inhibition of nitric oxide production
KPNA2	karyopherin subunit alpha 2	CaMK IV-mediated phosphorylation of CREB ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Sensing of DNA Double Strand Breaks Estrogen-dependent gene expression SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses
KPNB1	karyopherin subunit beta 1	ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Regulation of cholesterol biosynthesis by SREBP (SREBF) Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Nuclear import of Rev protein Nuclear import of Rev protein Initiation of Nuclear Envelope (NE) Reformation Neutrophil degranulation Assembly of the ORC complex at the origin of replication Interferon alpha/beta signaling Postmitotic nuclear pore complex (NPC) reformation Inhibition of nitric oxide production SARS-CoV-1 activates/modulates innate immune responses Maturation of hRSV A proteins
KRT1	keratin 1	Neutrophil degranulation Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	Zinc Copper Zinc acetate	Ichthyosis hystrix, Curth-Macklin type Epidermolytic palmoplantar keratoderma (EPPK) Striate palmoplantar keratoderma Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
KRT20	keratin 20	Keratinization Formation of the cornified envelope
KRT3	keratin 3	Keratinization Formation of the cornified envelope		Meesmann corneal dystrophy
KRT6A	keratin 6A	Keratinization Formation of the cornified envelope	Zinc Zinc acetate	Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
KRT6B	keratin 6B	Keratinization Formation of the cornified envelope		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
KRT75	keratin 75	Keratinization Formation of the cornified envelope		Pseudofolliculitis barbae
LMO2	LIM domain only 2	RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
LNX1	ligand of numb-protein X 1	Antigen processing: Ubiquitination & Proteasome degradation

Search Results for: NUP62