EXOSC8 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
HAPLN2	hyaluronan and proteoglycan link protein 2
HOXB9	homeobox B9
ILF2	interleukin enhancer binding factor 2	Neutrophil degranulation PKR-mediated signaling
INCA1	inhibitor of CDK, cyclin A1 interacting protein 1
KANK2	KN motif and ankyrin repeat domains 2
KCNJ11	potassium inwardly rectifying channel subfamily J member 11	ATP sensitive Potassium channels ABC-family proteins mediated transport Regulation of insulin secretion Ion homeostasis Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome Defective ABCC8 can cause hypo- and hyper-glycemias	Glimepiride Ibutilide Verapamil Tolazamide Ritodrine Levosimendan Glyburide Glyburide Diazoxide Thiamylal Yohimbine Butamben Isavuconazole	Permanent neonatal diabetes mellitus (PNDM) Transient neonatal diabetes mellitus (TNDM) Type II diabetes mellitus
LENG1	leukocyte receptor cluster member 1	mRNA Splicing - Major Pathway
LMO4	LIM domain only 4
LNX1	ligand of numb-protein X 1	Antigen processing: Ubiquitination & Proteasome degradation
LSM1	LSM1 homolog, mRNA degradation associated	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
LSM4	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
LSM7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
MACIR	macrophage immunometabolism regulator
METTL14	methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit	Processing of Capped Intron-Containing Pre-mRNA
MKRN1	makorin ring finger protein 1	AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
MORN4	MORN repeat containing 4
MRPL2	mitochondrial ribosomal protein L2	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
MTREX	Mtr4 exosome RNA helicase	Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Nuclear RNA decay
MYOZ1	myozenin 1
NEDD9	neural precursor cell expressed, developmentally down-regulated 9

Search Results for: EXOSC8